SCHEMBL6433342

SCHEMBL6433342

C=CC(=O)Oc1c(F)c(F)c2c(F)c(F)c(F)c(F)c2c1F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.36
TSHR P16473 2/20 0.31
HPGD P15428 1/20 0.31
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440095 0.92 THRB (0.33) THRB
SCHEMBL225748 0.92 THRB (0.40) THRBTSHRHPGDTHRA
SCHEMBL2579041 0.89 THRB (0.41) THRBTSHRHPGDTHRA
Acrylamide SCHEMBL28026684 0.84 TSHR (0.44) THRBTSHRHPGDTHRA
SCHEMBL1098070 0.83 THRB (0.38) THRBTSHRHPGDTHRA
SCHEMBL26363017 0.82 THRB (0.35) THRBTSHR
SCHEMBL26688609 0.82 THRB (0.35) THRBTSHR
SCHEMBL6436744 0.81 THRB (0.34) THRBTSHR
SCHEMBL8737374 0.81 THRB (0.34) THRB
SCHEMBL8733951 0.80 THRB (0.36) THRBTSHRHPGDTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8435610-B2 Copolymer of (meth)acrylic ester, composition, optical element and electric member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-05-07 US disclosed
US-8435610-B2 Copolymer of (meth)acrylic ester, composition, optical element and electric member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-05-07 US disclosed
US-20090264610-A1 Novel Copolymer of Methacrylic Ester, Composition, Optical Element and Electric Member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-10-22 US disclosed
US-20090264610-A1 Novel Copolymer of Methacrylic Ester, Composition, Optical Element and Electric Member JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-10-22 US disclosed
EP-1009729-B1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING & MFG (US) 2005-01-19 EP disclosed
US-6362379-B2 ACRYLATES HAVING HIGH DEGREE OF HALOGENATION AND POLYMERS USING THESE MONOMERS; USEFUL FOR OPTICAL WAVEGUIDES AND TELECOMMUNICATION 3M INNOVATIVE PROPERTIES COMPANY 2002-03-26 US disclosed
US-6313245-B1 USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2001-11-06 US disclosed
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom 3M INNOVATIVE PROPERTIES COMPANY 2001-11-01 US disclosed
US-6288266-B1 HALOGENATED ACRYLATES OR THIOACRYLATES FOR POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-09-11 US disclosed
CN-1259932-A Halogenated acrylates and polymers derived therefrom MINNESOTA MINING & MFG (US) 2000-07-12 CN disclosed
EP-1009729-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-06-21 EP disclosed
US-6005137-A POLYMERS USED IN OPTICAL DEVICES INCLUDING OPTICAL WAVEGUIDES AND INTERCONNECTING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-21 US disclosed
WO-1998056749-A1 HALOGENATED ACRYLATES AND POLYMERS DERIVED THEREFROM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037028-A1 Halogenated acrylates and polymers derived therefrom ZYX, ACR, ORMDL3 THRB 3639/4885TSHR 1965/4885HPGD 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.