SCHEMBL25793376

SCHEMBL25793376

Cc1ccc2c(c1)N(Cc1ccc(S(c3ccccc3)(c3ccccc3)c3ccccc3)cc1)C(C)(C)CC2C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.46
DRD4 P21917 2/20 0.46
AMPD2 Q01433 5/20 0.38
KDM4E B2RXH2 1/20 0.37
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847602 0.90 DRD2 (0.49) DRD2DRD4AMPD2KDM4ECRHBP
SCHEMBL25329514 0.84 DRD2 (0.46) DRD2DRD4AMPD2KDM4ECRHBP
SCHEMBL25244280 0.84 DRD2 (0.46) DRD2DRD4AMPD2KDM4ECRHBP
SCHEMBL25793382 0.81 AMPD2 (0.34) DRD2DRD4AMPD2KDM4ELMNA
SCHEMBL11783262 0.80 AMPD2 (0.50) DRD2DRD4AMPD2KDM4ECRHBP
SCHEMBL11783355 0.77 DRD2 (0.46) DRD2DRD4AMPD2LMNANPSR1
SCHEMBL9636472 0.76 AMPD2 (0.42) DRD2DRD4AMPD2KDM4ELMNA
SCHEMBL9847654 0.76 DRD2 (0.47) DRD2DRD4KDM4ECRHBPCRHR2
SCHEMBL8942319 0.75 DRD2 (0.46) DRD2DRD4KDM4ECRHBPCRHR2
SCHEMBL9073520 0.75 AMPD2 (0.49) DRD2DRD4AMPD2CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212399-A1 Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same LIGHTWAVE LOGIC, INC. (US) 2023-07-06 US disclosed