Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847654 | 0.88 | DRD2 (0.47) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL6141223 | 0.86 | DRD2 (0.43) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL30887165 | 0.84 | DRD2 (0.46) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL11183111 | 0.84 | DRD2 (0.46) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL596045 | 0.84 | DRD2 (0.46) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL9847643 | 0.84 | DRD2 (0.41) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL9847673 | 0.84 | DRD2 (0.41) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL9795985 | 0.84 | MAPT (0.36) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL8604280 | 0.84 | OPRM1 (0.36) | DRD2DRD4KDM4EMAPTCRHBP | |
| SCHEMBL9777041 | 0.83 | DRD2 (0.41) | DRD2DRD4KDM4EMAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0446731-B1 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0458746-A1 | Azo dyes, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1991-11-27 | — | — | EP | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0434611-A2 | Azo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| US-5013826-A | Azo dyes containing 5-cyclohexylcarbonyl-thiophene diazo components and 1,2,3,4-tetrahydroquinoline coupling components | CIBA-GIEGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| US-4552951-A | Disperse and acid azo dyes having one or two cinnamoyl substituents on a phenyl diazonium moiety and containing an aniline, tetrahydroquinoline or benzomorpholine coupler | EASTMAN KODAK COMPANY (US) | 1985-11-12 | — | — | US | disclosed |
| US-4530997-A | Containg quinoline or benzomorpholine coupler structure | EASTMAN KODAK COMPANY (US) | 1985-07-23 | — | — | US | disclosed |
| US-4283332-A | TEXTILES | EASTMAN KODAK COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-3998801-A | MONOAZO DYES; POLYAMIDES; RED TO VIOLET SHADES | EASTMAN KODAK COMPANY (US) | 1976-12-21 | — | — | US | disclosed |