Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | AMPD2 | Q01433 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244280 | 0.90 | DRD2 (0.46) | DRD2DRD4AMPD2KDM4ECRHBP | |
| SCHEMBL25793376 | 0.90 | DRD2 (0.46) | DRD2DRD4AMPD2KDM4ECRHBP | |
| SCHEMBL25329514 | 0.90 | DRD2 (0.46) | DRD2DRD4AMPD2KDM4ECRHBP | |
| SCHEMBL11783355 | 0.87 | DRD2 (0.46) | DRD2DRD4AMPD2LMNANPSR1 | |
| SCHEMBL9636472 | 0.85 | AMPD2 (0.42) | DRD2DRD4AMPD2KDM4ELMNA | |
| SCHEMBL9073520 | 0.85 | AMPD2 (0.49) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11783262 | 0.84 | AMPD2 (0.50) | DRD2DRD4AMPD2KDM4ECRHBP | |
| SCHEMBL31476440 | 0.84 | AMPD2 (0.39) | DRD2DRD4AMPD2CRHBPCRHR2 | |
| SCHEMBL11782496 | 0.84 | SIGMAR1 (0.45) | DRD2DRD4AMPD2ALDH1A1MAPT | |
| SCHEMBL8942319 | 0.82 | DRD2 (0.46) | DRD2DRD4KDM4ECRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434611-A2 | Azo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |