Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811017 | 1.00 | TSHR (0.51) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL25791250 | 0.87 | TSHR (0.39) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL25792539 | 0.87 | ALDH1A1 (0.44) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL24621958 | 0.86 | KMT2A (0.45) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL24811366 | 0.82 | TSHR (0.38) | TSHRKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL23729451 | 0.82 | TSHR (0.51) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL20470166 | 0.81 | CASP2 (0.53) | EPHX2 | |
| SCHEMBL19402659 | 0.81 | TSHR (0.58) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL26429056 | 0.81 | TSHR (0.58) | TSHRKDM4ELMNAHPGDMEN1 | |
| SCHEMBL18798616 | 0.81 | TSHR (0.58) | TSHRKDM4ELMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |