Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793462 | 0.91 | CASP2 (0.42) | ALDH1A1CASP2TSHRADRB2ADRB1 | |
| SCHEMBL25793454 | 0.90 | CASP2 (0.44) | CASP2TSHRNAAAMEN1KMT2A | |
| SCHEMBL19880188 | 0.86 | CASP2 (0.52) | ALDH1A1CASP2TSHRNAAAMEN1 | |
| SCHEMBL10038842 | 0.86 | CASP2 (0.48) | ALDH1A1CASP2TSHRNAAAMEN1 | |
| SCHEMBL29299613 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CASP2TSHRADRB2ADRB1 | |
| SCHEMBL19880208 | 0.81 | CASP2 (0.67) | CASP2NAAAMEN1KMT2AEPHX1 | |
| SCHEMBL29299599 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CASP2TSHRADRB2ADRB1 | |
| SCHEMBL14000019 | 0.81 | CASP2 (0.60) | ALDH1A1CASP2ADRB2NAAAMEN1 | |
| SCHEMBL25791250 | 0.81 | TSHR (0.39) | ALDH1A1CASP2TSHRADRB2ADRB1 | |
| SCHEMBL19350611 | 0.79 | CASP2 (0.57) | ALDH1A1CASP2TSHRNAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |