Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23742217 | 0.79 | CYP2D6 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL22606070 | 0.77 | CYP2D6 (0.31) | CYP2D6CYP2C19 | |
| SCHEMBL22256382 | 0.74 | CYP2D6 (0.42) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL25795525 | 0.72 | CYP2D6 (0.38) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL20070641 | 0.69 | CYP2D6 (0.34) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL24383368 | 0.69 | MLYCD (0.42) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL21884806 | 0.65 | — | — | |
| SCHEMBL13397365 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL7946066 | 0.63 | CYP2D6 (0.50) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL18624716 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861985-B1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES | OCULAR THERAPEUTIX INC (US) | 2023-06-14 | — | — | EP | disclosed |