Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.43 |
| ▸ | DDT | P30046 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.43 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792767 | 0.86 | UCHL5 (0.54) | EIF4EAKR1C3AKR1C2DDTUCHL5 | |
| SCHEMBL29952530 | 0.86 | UCHL5 (0.54) | EIF4EAKR1C3AKR1C2DDTUCHL5 | |
| SCHEMBL2574179 | 0.84 | MAPT (0.50) | EIF4ETSHRAKR1C3AKR1C2HNF4A | |
| SCHEMBL2556585 | 0.83 | NR1H4 (0.46) | EIF4EAKR1C3AKR1C2DDTUCHL5 | |
| SCHEMBL2556173 | 0.81 | SERPINE1 (0.51) | EIF4ETSHRRXRARXRBAKR1C3 | |
| SCHEMBL2371284 | 0.80 | HNF4A (0.63) | TSHRAKR1C3AKR1C2HNF4AAKR1C1 | |
| SCHEMBL2553756 | 0.79 | TNFRSF1A (0.46) | EIF4EAKR1C3AKR1C2DDTUCHL5 | |
| SCHEMBL2559218 | 0.79 | FOLH1 (0.48) | EIF4ERXRARXRBAKR1C3AKR1C2 | |
| SCHEMBL1449798 | 0.79 | MAPT (0.53) | AKR1C3AKR1C2NR1H4 | |
| SCHEMBL18936558 | 0.78 | DCLRE1B (0.49) | TSHRHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |