Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.42 |
| ▸ | CBLB | Q13191 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666351 | 0.80 | DDR1 (0.43) | DDR1ALDH1A1GAAL3MBTL1ANO1 | |
| SCHEMBL16093766 | 0.79 | ALDH1A1 (0.52) | DDR1ALDH1A1GAAL3MBTL1ANO1 | |
| SCHEMBL18422426 | 0.79 | KDR (0.54) | DDR1ALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL30595870 | 0.79 | KDR (0.54) | DDR1ALDH1A1GAAL3MBTL1POLB | |
| SCHEMBL25898677 | 0.79 | ALDH1A1 (0.48) | DDR1ALDH1A1GAAL3MBTL1ANO1 | |
| SCHEMBL25807049 | 0.77 | SMYD3 (0.43) | ALDH1A1L3MBTL1ANO1PYGLPYGM | |
| SCHEMBL25804854 | 0.75 | LRRK2 (0.43) | ANO1PYGLPYGM | |
| SCHEMBL25799171 | 0.75 | LOXL2 (0.40) | ANO1LOXL2 | |
| SCHEMBL25199807 | 0.74 | DDR1 (0.51) | DDR1ANO1TLR7ALKBH2ALKBH5 | |
| SCHEMBL16098050 | 0.74 | CFTR (0.55) | DDR1ALDH1A1GAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |