Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052090 | 0.86 | IDO1 (0.65) | IDO1CYP2A6HTTLOXL2MAOB | |
| SCHEMBL12835104 | 0.83 | IDO1 (0.61) | IDO1CYP2A6HTTLOXL2MAOB | |
| SCHEMBL6091888 | 0.83 | IDO1 (0.61) | IDO1CYP2A6HTTLOXL2MAOB | |
| SCHEMBL25798171 | 0.81 | IDO1 (0.46) | IDO1HTTNOS1ALDH1A1MAPT | |
| SCHEMBL850733 | 0.81 | IDO1 (1.00) | IDO1NOS1 | |
| Hydrochloric Acid SCHEMBL2943843 | 0.79 | IDO1 (0.96) | IDO1NOS1 | |
| Bromide SCHEMBL31060341 | 0.79 | IDO1 (1.00) | IDO1NOS1 | |
| SCHEMBL14423967 | 0.76 | IDO1 (0.71) | IDO1CYP2A6HTTLOXL2MAOB | |
| SCHEMBL24110955 | 0.75 | IDO1 (0.67) | IDO1NOS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1145998 | 0.75 | CYP2A6 (0.58) | IDO1CYP2A6HTTLOXL2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | BECN1, SQSTM1, ATG7 | IDO1 3758/4885CYP2A6 4421/4885HTT 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.