Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133892 | 0.84 | SLC11A2 (0.69) | IDO1SLC11A2TAAR1NOS1EPHX1 | |
| SCHEMBL25798168 | 0.81 | IDO1 (0.68) | IDO1NOS1ALDH1A1MAPTTSHR | |
| SCHEMBL4935305 | 0.78 | GLA (0.50) | GLADAOEPHX1TP53CTSB | |
| SCHEMBL28448952 | 0.77 | DAO (0.51) | GLADAOEPHX1TP53CTSB | |
| SCHEMBL19468248 | 0.75 | PKM (0.44) | GLADAOEPHX1TP53CTSB | |
| SCHEMBL18893133 | 0.75 | GLA (0.47) | GLADAOEPHX1TP53CTSB | |
| SCHEMBL15457418 | 0.75 | IDO1 (0.70) | IDO1SLC11A2TAAR1NOS1KMT2A | |
| SCHEMBL1140195 | 0.74 | IDO1 (0.61) | IDO1SLC11A2TAAR1NOS1ALDH1A1 | |
| SCHEMBL6617065 | 0.74 | GLA (0.54) | GLAGSK3BIDH1MEP1AMEP1B | |
| SCHEMBL18896283 | 0.74 | DAO (0.49) | GLADAOEPHX1TP53CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | HARVARD COLLEGE (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219898-A1 | COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY | BECN1, SQSTM1, ATG7 | IDO1 3758/4885SLC11A2 4694/4885GLA 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.