Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801607 | 0.86 | ROCK2 (0.43) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL25801593 | 0.84 | ROCK2 (0.42) | ROCK2ROCK1LMNATDP1MTNR1A | |
| SCHEMBL25801602 | 0.81 | ROCK2 (0.47) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL17132547 | 0.76 | LMNA (0.49) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL24474359 | 0.75 | ROCK2 (0.46) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL24474315 | 0.75 | ROCK2 (0.46) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL10270129 | 0.75 | ROCK2 (0.46) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL10270570 | 0.73 | ROCK2 (0.45) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL21168215 | 0.73 | LMNA (0.47) | ROCK2ROCK1LMNATDP1KMT2A | |
| SCHEMBL6267439 | 0.73 | ROCK2 (0.45) | ROCK2ROCK1LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | ROCK2 2310/4885ROCK1 1926/4885LMNA 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.