Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801607 | 0.91 | ROCK2 (0.43) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL25801600 | 0.84 | ROCK2 (0.44) | ROCK2ROCK1ALDH1A1TSHRLMNA | |
| SCHEMBL25801595 | 0.82 | ROCK2 (0.43) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL25801740 | 0.80 | NAAA (0.57) | ROCK2ROCK1ALDH1A1NAAAMAPT | |
| SCHEMBL24202420 | 0.79 | NAAA (0.64) | ALDH1A1NAAAMAPTGNAI3GNAO1 | |
| SCHEMBL25801598 | 0.79 | HSD17B10 (0.48) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL10270570 | 0.77 | ROCK2 (0.45) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL25801608 | 0.76 | ROCK2 (0.46) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL20900508 | 0.75 | NAAA (0.41) | ROCK2ROCK1ALDH1A1TSHRNAAA | |
| SCHEMBL10270126 | 0.75 | HSD17B10 (0.57) | ROCK2ROCK1ALDH1A1NAAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | ROCK2 2310/4885ROCK1 1926/4885ALDH1A1 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.