Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801628 | 0.66 | MEN1 (0.39) | — | |
| SCHEMBL14295543 | 0.64 | CA12 (0.34) | LMNASMN1; SMN2NPC1HTTRAB9A | |
| SCHEMBL8424721 | 0.60 | KMT2A (0.66) | LMNASMN1; SMN2 | |
| SCHEMBL13677614 | 0.58 | HTR6 (0.44) | SMN1; SMN2 | |
| SCHEMBL4566032 | 0.58 | HCRTR2 (0.48) | LMNAHTT | |
| SCHEMBL5273564 | 0.58 | — | — | |
| SCHEMBL14295196 | 0.57 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2NPC1GALR3NR2F2 | |
| SCHEMBL2055347 | 0.57 | VCAM1 (0.45) | LMNASMN1; SMN2HTT | |
| SCHEMBL435017 | 0.56 | — | — | |
| SCHEMBL13325688 | 0.56 | SLC9A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122600-A1 | PIPERAZINE INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED (US) | 2023-06-29 | — | — | WO | disclosed |