Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24202420 | 0.95 | NAAA (0.64) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL1679331 | 0.88 | NAAA (0.70) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL25801598 | 0.85 | HSD17B10 (0.48) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL10270570 | 0.83 | ROCK2 (0.45) | NAAAGNAI3GNAO1GNAI1MEN1 | |
| SCHEMBL25801595 | 0.83 | ROCK2 (0.43) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL17132547 | 0.82 | LMNA (0.49) | NAAAGNAI3GNAO1GNAI1KMT2A | |
| SCHEMBL377246 | 0.82 | NAAA (0.79) | NAAAGNAI3GNAO1GNAI1GAA | |
| SCHEMBL20900508 | 0.81 | NAAA (0.41) | NAAAGNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL22509724 | 0.81 | HSD17B10 (0.57) | NAAAGAAMEN1KMT2ACYP2C19 | |
| SCHEMBL10270126 | 0.81 | HSD17B10 (0.57) | NAAAGAAMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | NAAA 3354/4885GNAI3 2435/4885GNAO1 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.