SCHEMBL25801743

SCHEMBL25801743

CCCCCCCCc1nnc(CC(C(=O)OC(C)(C)C)P(C)(=O)OCC)o1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25804297 0.90 LMNA (0.41) LMNAMEN1TSHRKMT2AHTT
SCHEMBL25801937 0.84 MEN1 (0.33) LMNAMEN1TSHRKMT2A
SCHEMBL25801737 0.82 SRC (0.34)
SCHEMBL25801926 0.82 SRC (0.34)
SCHEMBL25801747 0.82 S1PR2 (0.32) LMNAMEN1TSHRKMT2A
SCHEMBL25801915 0.82 SRC (0.34)
SCHEMBL25801754 0.82 SRC (0.34)
SCHEMBL25801870 0.82 S1PR1 (0.31) LMNAMEN1TSHRKMT2A
SCHEMBL25801858 0.81 NPSR1 (0.43) LMNATSHRNPSR1POLBALDH1A1
SCHEMBL25801920 0.78 FDPS (0.36) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 LMNA 3388/4885MEN1 4504/4885TSHR 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.