SCHEMBL25801747

SCHEMBL25801747

CCCCCCCCc1nc(CC(C(=O)OC(C)(C)C)P(C)(=O)OCC)no1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.32
S1PR1 P21453 1/20 0.32
S1PR3 Q99500 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
SRC P12931 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25801754 0.92 SRC (0.34) SRC
SCHEMBL25801737 0.92 SRC (0.34) SRC
SCHEMBL25801915 0.92 SRC (0.34) SRC
SCHEMBL25801926 0.92 SRC (0.34) SRC
SCHEMBL25802066 0.85 PRSS1 (0.32) S1PR1S1PR3MEN1LMNAKMT2A
SCHEMBL25801813 0.84 SRC (0.33) S1PR2S1PR1S1PR3LPAR2MEN1
SCHEMBL25801968 0.83
SCHEMBL25801931 0.83
SCHEMBL25801930 0.83
SCHEMBL25801743 0.82 LMNA (0.41) MEN1LMNATSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 S1PR2 2797/4885S1PR1 2590/4885S1PR3 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.