SCHEMBL25801981

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25801987	0.94	SPHK1 (0.38)	S1PR1S1PR3FFAR1TP53MITF
	SCHEMBL23588176	0.92	S1PR4 (0.40)	S1PR4S1PR1S1PR5S1PR3FFAR1
	SCHEMBL25801780	0.90	SPHK1 (0.43)	S1PR4S1PR1S1PR5S1PR3FFAR1
	SCHEMBL25801802	0.89	SPHK1 (0.46)	S1PR1S1PR5S1PR3
	SCHEMBL25801989	0.87	SPHK1 (0.40)	FFAR1TP53MITFNCOA3RAB9A
	SCHEMBL23578053	0.86	SPHK1 (0.38)	S1PR1S1PR3FFAR1TP53MITF
	SCHEMBL25802138	0.86	LMNA (0.48)	ALDH1A1CYP1A2TSHRCYP2C19LMNA
	SCHEMBL25802076	0.86	RAB9A (0.38)	TP53HDAC4HDAC6RAB9ANPC1
	SCHEMBL25801976	0.86	CYP1A2 (0.39)	TP53MITFNCOA3HDAC4HDAC6
	SCHEMBL25802128	0.86	LMNA (0.39)	TP53MITFNCOA3RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.