Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801981 | 0.94 | S1PR4 (0.39) | HDAC8HDAC2HDAC1FFAR1S1PR1 | |
| SCHEMBL23578053 | 0.93 | SPHK1 (0.38) | SPHK1HDAC8HDAC2HDAC1FFAR1 | |
| SCHEMBL25801802 | 0.92 | SPHK1 (0.46) | SPHK1SPHK2S1PR2S1PR1S1PR3 | |
| SCHEMBL25801780 | 0.91 | SPHK1 (0.43) | SPHK1FFAR1SPHK2S1PR2S1PR1 | |
| SCHEMBL23588176 | 0.86 | S1PR4 (0.40) | HDAC8HDAC2HDAC1FFAR1S1PR1 | |
| SCHEMBL25801989 | 0.85 | SPHK1 (0.40) | SPHK1FFAR1MITFTP53NCOA3 | |
| SCHEMBL25801993 | 0.84 | RAB9A (0.37) | HDAC8HDAC2HDAC1TP53ALDH1A1 | |
| SCHEMBL25802138 | 0.84 | LMNA (0.48) | HDAC8HDAC2ALDH1A1TSHRLMNA | |
| SCHEMBL25802076 | 0.84 | RAB9A (0.38) | HDAC8HDAC2HDAC1TP53ALDH1A1 | |
| SCHEMBL23578218 | 0.84 | SPHK1 (0.47) | SPHK1FFAR1SPHK2S1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219907-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219907-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES | CPA2, RO60, C5AR1 | SPHK1 3875/4885HDAC8 2705/4885HDAC2 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.