Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257607 | 0.86 | CA1 (0.58) | MTNR1BMCL1CA1CA2SMN1; SMN2 | |
| SCHEMBL22960754 | 0.83 | ENPP2 (0.49) | CA2SMN1; SMN2F2ALDH1A1MEN1 | |
| SCHEMBL22212886 | 0.79 | CA1 (0.64) | CA1CA2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12260871 | 0.74 | ALDH1A1 (0.46) | MTNR1BMCL1SMN1; SMN2F2F10 | |
| SCHEMBL13064410 | 0.74 | PPARG (0.49) | MTNR1BSMN1; SMN2ACACBPTGS1ACACA | |
| SCHEMBL10269955 | 0.74 | MTNR1B (0.43) | MTNR1BMCL1SMN1; SMN2F2F10 | |
| SCHEMBL2968363 | 0.73 | RXRA (0.53) | CA2SMN1; SMN2ALDH1A1MEN1GAA | |
| Acetic Acid SCHEMBL4630472 | 0.72 | ALDH1A1 (0.61) | MTNR1BMCL1SMN1; SMN2ACACBMTNR1A | |
| SCHEMBL257918 | 0.71 | ENPP2 (0.65) | MTNR1BCA1CA2SMN1; SMN2MTNR1A | |
| SCHEMBL12663183 | 0.71 | ENPP2 (0.68) | MTNR1BCA1CA2SMN1; SMN2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |