SCHEMBL25802487

SCHEMBL25802487

Brc1ccc(N(c2ccc(Br)cc2)c2ccc(N3c4ccccc4N(Cc4ccc(N5c6ccccc6Nc6ccccc65)cc4)c4ccccc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
CNR1 P21554 2/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
EGFR P00533 2/20 0.33
PIM1 P11309 1/20 0.33
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
XBP1 P17861 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25802491 0.87 LMNA (0.39) LMNAHTTCNR1KDM4EPOLB
SCHEMBL19842099 0.78 LMNA (0.43) LMNAHTTCNR1KDM4EPOLB
SCHEMBL25802464 0.73 TP53 (0.45) LMNAHTTADRA1DADRA1AADRA1B
SCHEMBL27944411 0.70 FAAH (0.39) LMNAHTTCHRM5CHRM1CHRM3
SCHEMBL4571033 0.69 EGFR (0.56) LMNACHRM1EGFRPOLBGAA
SCHEMBL10482013 0.67 EGFR (0.57) LMNACHRM1EGFRPOLBEPHX2
SCHEMBL25802484 0.66 MEN1 (0.46) LMNACHRM1KDM4EMAPTGAA
SCHEMBL28415813 0.66 GNG2 (0.42) LMNAHTTCNR1KDM4EPOLB
SCHEMBL31168902 0.66 GNG2 (0.42) LMNAHTTCNR1KDM4EPOLB
SCHEMBL28647860 0.66 GNG2 (0.49) LMNAHTTCHRM1CNR1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692065-B2 Phenazine copolymers and uses thereof CORNELL UNIVERSITY (US) 2023-07-04 US disclosed