SCHEMBL25802491

SCHEMBL25802491

Brc1ccc(N(c2ccc(Br)cc2)c2ccc(N3c4ccccc4Nc4ccccc43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
HTT P42858 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.39
XBP1 P17861 1/20 0.39
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
GAA P10253 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
AKT1 P31749 1/20 0.33
GNG2 P59768 1/20 0.33
GNB1 P62873 1/20 0.33
CNR1 P21554 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19842099 0.90 LMNA (0.43) LMNAHTTKDM4EMAPTPOLB
SCHEMBL25802487 0.87 LMNA (0.39) LMNAHTTKDM4EMAPTPOLB
SCHEMBL31168902 0.75 GNG2 (0.42) LMNAHTTKDM4EMAPTPOLB
SCHEMBL28647860 0.75 GNG2 (0.49) LMNAHTTKDM4EMAPTPOLB
SCHEMBL28415813 0.75 GNG2 (0.42) LMNAHTTKDM4EMAPTPOLB
SCHEMBL31423808 0.74 GNG2 (0.49) HTTKDM4EMAPTPOLBMGLL
SCHEMBL1264195 0.74 GNG2 (0.49) HTTKDM4EMAPTPOLBMGLL
Hydrochloric Acid SCHEMBL30544630 0.73 GNG2 (0.47) HTTKDM4EMAPTPOLBMGLL
SCHEMBL24457995 0.72 ALDH1A1 (0.50) HTTKDM4EMAPTPOLBMGLL
SCHEMBL15470446 0.72 FAAH (0.47) FAAHMGLLGAASMN1; SMN2AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692065-B2 Phenazine copolymers and uses thereof CORNELL UNIVERSITY (US) 2023-07-04 US disclosed