SCHEMBL2580853

SCHEMBL2580853

CC(O)C(NC(=O)CCCCC(S)CCS)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.43
MME P08473 2/20 0.36
NOD1 Q9Y239 1/20 0.35
EPHX2 P34913 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
SLC6A5 Q9Y345 1/20 0.34
PLA2G10 O15496 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580857 1.00 FAAH (0.43) FAAHMMENOD1EPHX2MEN1
Zinc Ion SCHEMBL2582011 0.85 FAAH (0.35) FAAHMEN1KMT2AMAPK1
SCHEMBL2583386 0.84 FAAH (0.41) FAAHMMEPLA2G10
SCHEMBL2583384 0.84 FAAH (0.41) FAAHMMEPLA2G10
SCHEMBL2580940 0.84 FAAH (0.56) FAAHMMENOD1MEN1KMT2A
SCHEMBL2580938 0.84 FAAH (0.56) FAAHMMENOD1MEN1KMT2A
SCHEMBL15969793 0.83 FAAH (0.44) FAAHMMENOD1EPHX2MEN1
SCHEMBL29165688 0.83 FAAH (0.44) FAAHMMENOD1EPHX2MEN1
SCHEMBL2582839 0.82 KMT2A (0.53) FAAHNOD1EPHX2MEN1KMT2A
SCHEMBL2576072 0.80 KMT2A (0.51) FAAHNOD1EPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US claimed
CN-1681490-A Melanin extinguisher OGA RES INC (JP) 2005-10-12 CN claimed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP claimed
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
CN-100367949-C Melanin extinguisher OGA RES INC (JP) 2008-02-13 CN disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
CN-1681490-A Melanin extinguisher OGA RES INC (JP) 2005-10-12 CN disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF FAAH 4202/4885MME 259/4885NOD1 4616/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 FAAH 3678/4885MME 50/4885NOD1 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.