SCHEMBL2583384

SCHEMBL2583384

CC(O)C(NC(=O)CCCCC(S)CCS)C(=O)NCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PTGS2 P35354 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTPN1 P18031 1/20 0.39
PTGS1 P23219 1/20 0.38
GSTK1 Q9Y2Q3 1/20 0.38
MME P08473 2/20 0.37
ACE P12821 2/20 0.37
CPA1 P15085 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
GLO1 Q04760 1/20 0.32
PLA2G10 O15496 1/20 0.32
ECE1 P42892 1/20 0.32
NMT2 O60551 1/20 0.32
NMT1 P30419 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2583386 1.00 FAAH (0.41) FAAHALDH1A1LMNAMAPTPTGS2
Zinc Ion SCHEMBL2577653 0.87 FAAH (0.31) FAAHNMT2NMT1
SCHEMBL2580853 0.84 FAAH (0.43) FAAHMMEPLA2G10
SCHEMBL2580857 0.84 FAAH (0.43) FAAHMMEPLA2G10
SCHEMBL2576056 0.80 PTGS1 (0.48) FAAHALDH1A1LMNAMAPTPTGS2
SCHEMBL2576057 0.80 PTGS1 (0.48) FAAHALDH1A1LMNAMAPTPTGS2
SCHEMBL2580508 0.80 PTPN1 (0.54) FAAHALDH1A1LMNAMAPTPTGS2
SCHEMBL3283754 0.79 PTPN1 (0.53) FAAHALDH1A1LMNAMAPTPTGS2
SCHEMBL3335091 0.79 PTPN1 (0.53) FAAHALDH1A1LMNAMAPTPTGS2
Zinc Ion SCHEMBL2582011 0.79 FAAH (0.35) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US claimed
CN-1681490-A Melanin extinguisher OGA RES INC (JP) 2005-10-12 CN claimed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP claimed
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
CN-100367949-C Melanin extinguisher OGA RES INC (JP) 2008-02-13 CN disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
CN-1681490-A Melanin extinguisher OGA RES INC (JP) 2005-10-12 CN disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF FAAH 4202/4885ALDH1A1 551/4885LMNA 4485/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 FAAH 3678/4885ALDH1A1 356/4885LMNA 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.