SCHEMBL2580940

SCHEMBL2580940

C[C@H](NC(=O)CCCCC(S)CCS)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.56
SMN1; SMN2 Q16637 2/20 0.43
SLC6A5 Q9Y345 1/20 0.43
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.40
MME P08473 2/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
NOD1 Q9Y239 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPK1 P28482 1/20 0.38
PLA2G10 O15496 2/20 0.35
PLA2G2C Q5R387 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580938 1.00 FAAH (0.56) FAAHSMN1; SMN2SLC6A5ALDH1A1MAPT
SCHEMBL2582839 0.85 KMT2A (0.53) FAAHSMN1; SMN2ALDH1A1NOD1MEN1
SCHEMBL2576072 0.84 KMT2A (0.51) FAAHSMN1; SMN2ALDH1A1NOD1MEN1
Zinc Ion SCHEMBL2582837 0.84 FAAH (0.40) FAAHSMN1; SMN2SLC6A5NOD1MEN1
SCHEMBL2580857 0.84 FAAH (0.43) FAAHSLC6A5MMENOD1MEN1
SCHEMBL2580853 0.84 FAAH (0.43) FAAHSLC6A5MMENOD1MEN1
SCHEMBL2581221 0.81 FOLH1 (0.45) FAAHSMN1; SMN2SLC6A5MAPTACE
SCHEMBL2581219 0.81 FOLH1 (0.45) FAAHSMN1; SMN2SLC6A5MAPTACE
SCHEMBL9550539 0.81 FAAH (0.66) FAAHSMN1; SMN2SLC6A5ALDH1A1MAPT
SCHEMBL15602675 0.81 FAAH (0.66) FAAHSMN1; SMN2SLC6A5ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US claimed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP claimed
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF FAAH 4202/4885SMN1; SMN2 1519/4885SLC6A5 2176/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 FAAH 3678/4885SMN1; SMN2 1975/4885SLC6A5 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.