Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840868 | 0.83 | CYP2C19 (0.48) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL514501 | 0.81 | ALDH1A1 (0.58) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL2578117 | 0.79 | ALDH1A1 (0.55) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL4916965 | 0.79 | POLB (0.53) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL2581202 | 0.78 | ALDH1A1 (0.53) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL6953167 | 0.78 | ALDH1A1 (0.54) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL1666014 | 0.78 | ALDH1A1 (0.56) | CYP2C19POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL1665641 | 0.78 | ALDH1A1 (0.56) | CYP2C19POLBALDH1A1KMT2AMEN1 | |
| SCHEMBL19214784 | 0.77 | ALDH1A1 (0.53) | CYP2C19POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL18157988 | 0.76 | ALDH1A1 (0.46) | CYP2C19POLBALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048825-B2 | Haloalkylsulfonanilide derivatives or salt thereof, herbicide comprising the derivatives as active ingredient, and use of the herbicide | NIHON NOHYAKU CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| CN-101535283-B | Haloalkylsulfonanilide derivative or salt thereof, herbicide containing the derivative as active ingredient, and use of the herbicide | NIHON NOHYAKU CO LTD | 2011-08-17 | — | — | CN | disclosed |
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| CN-101535283-A | Haloalkylsulfonanilide derivative or salt thereof, herbicide containing the derivative as active ingredient, and use of the herbicide | NIHON NOHYAKU CO LTD (JP) | 2009-09-16 | — | — | CN | disclosed |
| EP-2085392-A1 | HALOALKYLSULFONANILIDE DERIVATIVE OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | Nihon Nohyaku CO., LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | HDHD5, CBR3, DHRS9 | CYP2C19 582/4885POLB 3398/4885ALDH1A1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.