SCHEMBL2580928

SCHEMBL2580928

CC(C)(c1ccc(OC#N)cc1)c1ccc(Oc2ccc(C(C)(C)c3ccc(OC#N)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.42
MAPT P10636 5/20 0.42
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MAPK1 P28482 1/20 0.42
TSHR P16473 3/20 0.37
AR P10275 3/20 0.37
ESR1 P03372 2/20 0.37
CYP3A4 P08684 2/20 0.37
ESR2 Q92731 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
HTR6 P50406 1/20 0.37
ESRRG P62508 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TP53 P04637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789786 0.94 HPGD (0.41) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL25961 0.94 HPGD (0.41) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL1555244 0.94 HPGD (0.41) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL12877825 0.90 POLB (0.43) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL28080725 0.88 RAB9A (0.42) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL22966364 0.88 KIF11 (0.42) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL22966431 0.88 KIF11 (0.42) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL20547222 0.88 KIF11 (0.42) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL15630843 0.88 ALDH1A1 (0.44) HPGDMAPTALDH1A1NPC1RAB9A
SCHEMBL2586433 0.87 HTT (0.44) HPGDMAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664341-B2 Vinylbenzyl ethers of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES, LLC (US) 2014-03-04 US disclosed
US-8519066-B2 Poly(allyl ethers) of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-27 US disclosed
US-20130211015-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-15 US disclosed
EP-2563755-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
EP-2563756-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
US-20130041114-A1 POLY(ALLYL ETHERS) OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-14 US disclosed
WO-2011136847-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
WO-2011136845-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
US-5605781-A Photosensitive composition with cyanate esters and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1997-02-25 US disclosed
US-5464726-A Making resist image by exposing positive photosensitive composition /cyanate ester and cationic photoinitiator generating Bronsted acid upon exposure to actinic light/ in predetermined pattern to actinic light, heating, developing INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1995-11-07 US disclosed
WO-1985003713-A1 A PROCESS FOR THE PREPARATION OF POLYTRIAZINES FROM AROMATIC POLYCYANATES THE DOW CHEMICAL COMPANY (US) 1985-08-29 WO disclosed
EP-0147548-A2 Novel polyaromatic cyanates and polytriazines prepared therefrom THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
US-4528366-A Production of polytriazines from aromatic polycyanates with cobalt salt of a carboxylic acid as catalyst THE DOW CHEMICAL COMPANY (US) 1985-07-09 US disclosed
WO-1985002184-A1 POLYAROMATIC CYANATES, A PROCESS FOR PREPARING THE POLYAROMATIC CYANATES, AND POLYTRIAZINES PREPARED FROM THE POLYAROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
WO-1985002185-A1 A PROCESS FOR THE PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
US-4195132-A CROSSLINKING BY WAT OF TRIAZINE RINGS BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4116946-A OLEFIN, CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4094852-A Process for the production of polytriazines in the presence of high-boiling esters BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed