Zinc Ion

Zinc Ion

SCHEMBL2582837

C[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].C[C@H](NC(=O)CCCCC(S)CCS)C(=O)[O-].[NaH].[Zn+2]

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.40
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
MAPK1 P28482 1/20 0.35
PLA2G10 O15496 2/20 0.31
CA1 P00915 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CPT2 P23786 1/20 0.30
CPT1A P50416 1/20 0.30
CPT1B Q92523 1/20 0.30
SLC6A5 Q9Y345 1/20 0.30
NOD1 Q9Y239 1/20 0.30
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL2582011 0.85 FAAH (0.35) FAAHKMT2AMEN1MAPK1
SCHEMBL2580938 0.84 FAAH (0.56) FAAHKMT2AMEN1MAPK1PLA2G10
SCHEMBL2580940 0.84 FAAH (0.56) FAAHKMT2AMEN1MAPK1PLA2G10
Zinc Ion SCHEMBL2583762 0.82 PRSS1 (0.32) KMT2AMEN1
Zinc Ion SCHEMBL2585203 0.82 NMT1 (0.34) KMT2AMEN1NOD1
SCHEMBL2582839 0.82 KMT2A (0.53) FAAHKMT2AMEN1MAPK1PLA2G10
Zinc Ion SCHEMBL2574083 0.81 NOD1 (0.44) FAAHKMT2AMEN1MAPK1CPT2
Zinc Ion SCHEMBL2577660 0.81 KMT2A (0.33) KMT2AMEN1SLC6A5NOD1
Zinc Ion SCHEMBL2580359 0.81 EPHX2 (0.42) KMT2ACPT2CPT1ACPT1BNOD1
SCHEMBL2576072 0.80 KMT2A (0.51) FAAHKMT2AMEN1MAPK1PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF FAAH 4202/4885KMT2A 1597/4885MEN1 492/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 FAAH 3678/4885KMT2A 1749/4885MEN1 435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.