Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 13/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809331 | 0.93 | CYP2D6 (0.64) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL21393286 | 0.87 | CYP2D6 (0.68) | CYP2D6CYP3A4ALDH1A1USP2TSHR | |
| SCHEMBL16600547 | 0.86 | CYP2D6 (0.66) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL4927933 | 0.86 | CYP2D6 (0.69) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL9510221 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPK1TSHR | |
| SCHEMBL2381838 | 0.81 | CYP2D6 (0.67) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL25809447 | 0.81 | CYP3A4 (0.65) | CYP2D6CYP3A4ALDH1A1USP2TSHR | |
| SCHEMBL16431003 | 0.80 | CYP2D6 (0.78) | CYP2D6CHRM2CHRM3CYP3A4ALDH1A1 | |
| SCHEMBL25809386 | 0.79 | CHRM2 (0.54) | CYP2D6CHRM2CYP3A4ALDH1A1USP2 | |
| SCHEMBL25809385 | 0.79 | CYP3A4 (0.48) | CYP2D6CYP3A4USP2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |