Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 19/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 17/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809331 | 0.87 | CYP2D6 (0.64) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809386 | 0.86 | CHRM2 (0.54) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809441 | 0.82 | GPR183 (0.58) | CYP3A4CYP2D6TSHR | |
| SCHEMBL21393286 | 0.81 | CYP2D6 (0.68) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809456 | 0.81 | CYP2D6 (0.63) | CYP3A4CYP2D6CYP2C19ALDH1A1USP2 | |
| SCHEMBL25809390 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809381 | 0.80 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809438 | 0.80 | ALDH1A1 (0.52) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL25809389 | 0.80 | ALDH1A1 (0.48) | CYP3A4CYP2D6CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL31565342 | 0.79 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |