Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809331 | 0.86 | CYP2D6 (0.64) | CYP3A4CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809441 | 0.83 | GPR183 (0.58) | CYP3A4CYP2D6TSHRFAAH | |
| SCHEMBL21393286 | 0.80 | CYP2D6 (0.68) | CYP3A4CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809383 | 0.80 | FAAH (0.48) | CYP3A4CYP2D6TSHRFAAHCYP1A2 | |
| SCHEMBL25809456 | 0.79 | CYP2D6 (0.63) | CYP3A4CYP2D6TSHRCYP2C19USP2 | |
| SCHEMBL25809447 | 0.79 | CYP3A4 (0.65) | CYP3A4CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809445 | 0.78 | DOCK5 (0.49) | CYP3A4CYP2D6TSHRCYP1A2KMT2A | |
| SCHEMBL25809386 | 0.77 | CHRM2 (0.54) | CYP3A4CYP2D6TSHRFAAHCYP1A2 | |
| SCHEMBL25809390 | 0.77 | CYP3A4 (0.46) | CYP3A4CYP2D6TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809381 | 0.76 | CYP3A4 (0.50) | CYP3A4CYP2D6TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |