Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 12/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393286 | 0.94 | CYP2D6 (0.68) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809456 | 0.93 | CYP2D6 (0.63) | CYP2D6CYP3A4TSHRCYP2C19USP2 | |
| SCHEMBL25809447 | 0.87 | CYP3A4 (0.65) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL4692167 | 0.86 | CYP2D6 (0.70) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809386 | 0.86 | CHRM2 (0.54) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809385 | 0.86 | CYP3A4 (0.48) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809441 | 0.84 | GPR183 (0.58) | CYP2D6CYP3A4TSHR | |
| SCHEMBL25809390 | 0.83 | CYP3A4 (0.46) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809438 | 0.82 | ALDH1A1 (0.52) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 | |
| SCHEMBL25809381 | 0.82 | CYP3A4 (0.50) | CYP2D6CYP3A4TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |