Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 4/20 | 0.55 |
| ▸ | CCND1 | P24385 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257765 | 0.86 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL31021 | 0.85 | HTR6 (0.73) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL29509279 | 0.85 | HTR6 (0.73) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL2247137 | 0.84 | HTR6 (0.72) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL29459650 | 0.84 | HTR6 (0.72) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL6086778 | 0.83 | HTR6 (0.66) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL30914586 | 0.83 | HTR6 (0.66) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL6087734 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL21335591 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL3844137 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | SOOCHOW UNIVERSITY (CN) | 2018-07-19 | — | — | US | disclosed |
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | SOOCHOW UNIVERSITY (CN) | 2018-07-19 | — | — | US | disclosed |
| WO-2017215110-A1 | SYNTHETIC METHOD FOR ASYMMETRICAL THIOETHER | 苏州大学 | 2017-12-21 | — | — | WO | disclosed |
| US-8048897-B2 | Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-11-01 | — | — | US | disclosed |
| CN-101010276-B | Cyclohexane derivative, prodrug thereof, salt thereof, and therapeutic agent for diabetes containing same | CHUGAI PHARMACEUTICAL CO LTD | 2011-01-12 | — | — | CN | disclosed |
| US-20080318874-A1 | Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-12-25 | — | — | US | disclosed |
| CN-101010276-A | Novel cyclohexane derivative, prodrug thereof, salt thereof, and therapeutic agent for diabetes containing the same | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-08-01 | — | — | CN | disclosed |
| EP-1783110-A1 | NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201576-A1 | METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER | STS, TST, SCLY | HTR6 4374/4885KMT2A 1995/4885PLAU 1197/4885 |
| US-20080318874-A1 | Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes | SLC5A1, GPR119, SLC5A2 | HTR6 2254/4885KMT2A 1594/4885PLAU 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.