Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810460 | 0.78 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2KDM4EALOX15 | |
| SCHEMBL18830602 | 0.77 | ATM (0.58) | ALDH1A1NAMPTNPC1SMN1; SMN2ATM | |
| SCHEMBL11948184 | 0.77 | ATM (0.52) | ALDH1A1NAMPTNPC1SMN1; SMN2ATM | |
| SCHEMBL3918700 | 0.75 | ATM (0.56) | ALDH1A1NAMPTNPC1SMN1; SMN2ATM | |
| SCHEMBL23210729 | 0.75 | NAMPT (0.37) | ALDH1A1NAMPTNPC1ACKR3TACR1 | |
| SCHEMBL16015485 | 0.73 | HTR1A (0.46) | ALDH1A1NAMPTNPC1ACKR3SMN1; SMN2 | |
| SCHEMBL25824934 | 0.73 | NPC1 (0.46) | ALDH1A1POLBNAMPTNPC1SMN1; SMN2 | |
| SCHEMBL2481091 | 0.73 | NPC1 (0.41) | ALDH1A1NAMPTNPC1ACKR3SMN1; SMN2 | |
| SCHEMBL24733577 | 0.73 | NPC1 (0.35) | NAMPTNPC1SIGMAR1 | |
| SCHEMBL16116722 | 0.73 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |