Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17176221 | 0.88 | KDM4E (0.39) | ALDH1A1KDM4ERORCPIK3R1PIK3CA | |
| SCHEMBL25840967 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EPIK3R1PIK3CA | |
| SCHEMBL27306319 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ERORCALOX15POLB | |
| SCHEMBL25810457 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4EALOX15POLBSMN1; SMN2 | |
| SCHEMBL16116722 | 0.76 | ALDH1A1 (0.68) | ALDH1A1ALOX15POLB | |
| SCHEMBL15335166 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EALOX15POLBGRIN2B | |
| SCHEMBL11837217 | 0.74 | ALDH1A1 (0.52) | ALDH1A1ALOX15POLBSMN1; SMN2 | |
| SCHEMBL22900090 | 0.74 | ALDH1A1 (0.43) | ALDH1A1ALOX15POLBGRIN2BSMN1; SMN2 | |
| SCHEMBL4630504 | 0.74 | ATM (0.50) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11948185 | 0.74 | ATM (0.44) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250513-A1 | 13-MEMBERED MACROLIDE COMPOUNDS FOR TREATING DISEASES MEDIATED BY ABNORMAL PROTEIN TRANSLATION | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |