SCHEMBL25810727

SCHEMBL25810727

CCCCc1ccc(-n2c3ccccc3c3cc(-c4cccc(-c5ccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)cc5)c4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.45
KAT2A Q92830 1/20 0.45
KAT2B Q92831 1/20 0.45
TSPO P30536 2/20 0.45
HSD11B1 P28845 2/20 0.44
KDM4E B2RXH2 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
PTPN1 P18031 1/20 0.40
DHODH Q02127 1/20 0.39
CTSV O60911 1/20 0.39
CTSL P07711 1/20 0.39
RARB P10826 1/20 0.38
PTGER4 P35408 1/20 0.38
IL1R1 P14778 1/20 0.38
EIF4A1 P60842 1/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22617849 0.97 HSD11B1 (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL25919842 0.96 EP300 (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL25798357 0.96 EP300 (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL25810829 0.95 TSPO (0.45) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL24303761 0.94 TSPO (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL24303959 0.94 EP300 (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL24914710 0.93 TSPO (0.43) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL24303899 0.93 TSPO (0.43) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL24737169 0.93 TSPO (0.44) EP300KAT2AKAT2BTSPOHSD11B1
SCHEMBL26705774 0.93 KDM4E (0.45) EP300KAT2AKAT2BTSPOHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217820-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217820-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, SOD1, TERT EP300 3897/4885KAT2A 3721/4885KAT2B 2675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.