Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.44 |
| ▸ | XPO1 | O14980 | 2/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330354 | 0.91 | MAPT (0.55) | MAPTKIF11RAPGEF4XPO1IDH2 | |
| Hydrochloric Acid SCHEMBL1968509 | 0.89 | MAPT (0.53) | MAPTKIF11RAPGEF4XPO1IDH2 | |
| SCHEMBL8116484 | 0.89 | GABRA1 (0.48) | MAPTKIF11GABRA1GABRB2ALDH1A1 | |
| SCHEMBL20082558 | 0.84 | GABRA1 (0.42) | MAPTKIF11GABRA1GABRB2ALDH1A1 | |
| SCHEMBL1104677 | 0.83 | GABRB2 (0.52) | MAPTKIF11RAPGEF4XPO1GABRA1 | |
| SCHEMBL22861023 | 0.83 | GABRB2 (0.52) | MAPTKIF11RAPGEF4XPO1GABRA1 | |
| SCHEMBL13181873 | 0.80 | RAPGEF4 (0.55) | MAPTKIF11RAPGEF4XPO1IDH2 | |
| SCHEMBL3439602 | 0.79 | RAPGEF4 (0.48) | MAPTKIF11RAPGEF4XPO1GABRA1 | |
| SCHEMBL25005829 | 0.78 | MEN1 (0.35) | MAPTKIF11RAPGEF4GABRA1GABRB2 | |
| SCHEMBL7944387 | 0.78 | KIF11 (0.45) | MAPTKIF11RAPGEF4XPO1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |