Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811878 | 0.82 | MEN1 (0.35) | MEN1GLAKMT2AGAAKDM4E | |
| SCHEMBL25811610 | 0.82 | NR1I2 (0.32) | NR1I2ALDH1A1LMNACYP2C9ALOX15 | |
| SCHEMBL25826693 | 0.81 | MEN1 (0.34) | MEN1GLAKMT2AGAAKDM4E | |
| SCHEMBL25826699 | 0.78 | MEN1 (0.33) | MEN1GLAKMT2AGAAKDM4E | |
| SCHEMBL25811617 | 0.78 | MEN1 (0.33) | MEN1GLAKMT2AGAAKDM4E | |
| SCHEMBL25826782 | 0.69 | ALDH1A1 (0.35) | KDM4ENR1I2ALDH1A1LMNACYP1A2 | |
| SCHEMBL25811601 | 0.61 | CYP3A4 (0.33) | CYP3A4ALOX15 | |
| SCHEMBL25811605 | 0.61 | — | — | |
| Propane SCHEMBL28487756 | 0.59 | CA2 (0.61) | MEN1KMT2AGAAKDM4ENR1I2 | |
| SCHEMBL19296761 | 0.58 | ALDH1A1 (0.39) | MEN1KMT2AGAAKDM4ENR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |