Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811620 | 0.82 | MEN1 (0.33) | NR1I2ALDH1A1LMNACYP2C9ALOX15 | |
| SCHEMBL25811605 | 0.79 | — | — | |
| SCHEMBL25826782 | 0.72 | ALDH1A1 (0.35) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL25811601 | 0.64 | CYP3A4 (0.33) | ALOX15 | |
| SCHEMBL25811878 | 0.62 | MEN1 (0.35) | NR1I2ALDH1A1LMNACYP2C9ALOX15 | |
| SCHEMBL25811593 | 0.61 | — | — | |
| SCHEMBL19296761 | 0.60 | ALDH1A1 (0.39) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL27309280 | 0.59 | KDM1A (0.36) | — | |
| SCHEMBL28803391 | 0.59 | ALOX15 (0.50) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL39962 | 0.58 | CA2 (0.70) | NR1I2ALDH1A1LMNACYP2C9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |