Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811441 | 0.80 | DPP7 (0.48) | HTR6PTGDRPTGDR2SIGMAR1 | |
| SCHEMBL25811430 | 0.74 | PTGDR2 (0.51) | HTR6PTGDRPTGDR2AVPR1A | |
| SCHEMBL25811446 | 0.70 | HTR6 (0.42) | HTR6PTGDRPTGDR2 | |
| SCHEMBL24015624 | 0.68 | HTR6 (0.52) | HTR6PTGDRPTGDR2 | |
| SCHEMBL25811424 | 0.68 | HTR6 (0.50) | HTR6PTGDRPTGDR2 | |
| SCHEMBL25811425 | 0.67 | PTGDR2 (0.47) | HTR6PTGDRPTGDR2 | |
| SCHEMBL19605706 | 0.67 | HTR6 (0.50) | HTR6PTGDRPTGDR2AVPR1A | |
| SCHEMBL25811440 | 0.66 | PTGDR2 (0.46) | HTR6PTGDRPTGDR2 | |
| SCHEMBL30312304 | 0.65 | SIGMAR1 (0.48) | HTR6SIGMAR1 | |
| SCHEMBL25811426 | 0.65 | SIGMAR1 (0.48) | HTR6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218573-A1 | INDOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | GALYAN BIO INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218573-A1 | INDOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | HTT, HYPK, PARK7 | HTR6 14/4885PTGDR 3816/4885PTGDR2 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.