Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952309 | 0.84 | CDK9 (0.48) | CDK9DYRK1AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL24021017 | 0.84 | CDK9 (0.54) | CDK9DYRK1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30310501 | 0.84 | CDK9 (0.54) | CDK9DYRK1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL25789988 | 0.82 | MMP13 (0.50) | CDK9DYRK1AMTNR1AMTNR1BTSHR | |
| SCHEMBL23835767 | 0.80 | CDK9 (0.45) | CDK9DYRK1AMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL24450337 | 0.79 | DYRK1A (0.41) | CDK9DYRK1ASMN1; SMN2KDM4EHRH4 | |
| SCHEMBL23836116 | 0.78 | TSHR (0.46) | CDK9DYRK1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24740174 | 0.77 | MAOB (0.51) | MTNR1AMTNR1BIDO1SMN1; SMN2MEN1 | |
| SCHEMBL31345741 | 0.76 | SMN1; SMN2 (0.46) | CDK9DYRK1ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6650617 | 0.73 | CDK9 (0.46) | CDK9DYRK1ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | CDK9 756/4885DYRK1A 3984/4885MTNR1A 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.