SCHEMBL2581501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136167	0.86	MAOB (0.39)	MAOBPTGS2MAOAMAPK13MAPK12
	SCHEMBL1136308	0.85	MAOB (0.39)	MAOBPTGS2MAOAMAPK13MAPK12
	SCHEMBL1136380	0.84	MAOB (0.39)	ERN1MAOBPTGS2MAOAMAPK13
	SCHEMBL2492254	0.84	MAOB (0.37)	ERN1MAOBPTGS2MAOAMAPK13
	SCHEMBL1136363	0.84	MAOB (0.37)	MAOBPTGS2MAOAMAPK13MAPK12
	SCHEMBL2461285	0.83	PTGS2 (0.40)	MAOBPTGS2MGAMGAASI
	SCHEMBL2462830	0.82	PTGS2 (0.38)	MAOBPTGS2MAOAMGAMGAA
	SCHEMBL2588854	0.80	MAOB (0.33)	MAOBPTGS2MAOAMAPK13MAPK12
	SCHEMBL2584544	0.80	NEK1 (0.34)	MAOBMAPK13MAPK12MAPK11MAPK14
	SCHEMBL2489056	0.80	MGAM (0.34)	MAOBPTGS2MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.