SCHEMBL2461285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2462830	0.91	PTGS2 (0.38)	PTGS2EDNRBMAOBDHODHGAA
	SCHEMBL2588809	0.86	ACR (0.39)	PTGS2CNR2GAAKDM4ESMN1; SMN2
	SCHEMBL1136167	0.85	MAOB (0.39)	PTGS2MAOBGAAMGAMSI
	SCHEMBL12175984	0.85	CNR2 (0.36)	PTGS2MAOBCNR2GAAKDM4E
	SCHEMBL12160578	0.85	GYS1 (0.39)	PTGS2MAOBKEAP1NFE2L2GAA
	SCHEMBL2492254	0.85	MAOB (0.37)	PTGS2CHRM1MAOBKEAP1NFE2L2
	SCHEMBL1136308	0.85	MAOB (0.39)	PTGS2MAOBGAAMGAMSI
	SCHEMBL2463127	0.83	PTGS2 (0.39)	PTGS2MAOBKEAP1NFE2L2GAA
	SCHEMBL1136363	0.83	MAOB (0.37)	PTGS2MAOBCNR2GAAKDM4E
	SCHEMBL2581501	0.83	ERN1 (0.38)	PTGS2MAOBGAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.