SCHEMBL2584544

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2584541	0.88	MTNR1A (0.39)	MTNR1AMTNR1BCNR1
	SCHEMBL2588854	0.86	MAOB (0.33)	NEK1MTNR1AMTNR1BMAPK13MAPK12
	SCHEMBL2581569	0.85	KDM4E (0.34)	NEK1MTNR1AMTNR1BMAPK13MAPK12
	SCHEMBL1136308	0.85	MAOB (0.39)	MAPK13MAPK12MAPK11MAPK14MAOB
	SCHEMBL2463127	0.85	PTGS2 (0.39)	MTNR1AMTNR1BMAOB
	SCHEMBL2492254	0.83	MAOB (0.37)	MTNR1AMTNR1BMAPK13MAPK12MAPK11
	SCHEMBL2585468	0.83	PDE3B (0.36)	MTNR1AMTNR1BFPR1
	SCHEMBL1136167	0.80	MAOB (0.39)	MAPK13MAPK12MAPK11MAPK14MAOB
	SCHEMBL2581501	0.80	ERN1 (0.38)	MAPK13MAPK12MAPK11MAPK14MAOB
	SCHEMBL2578823	0.78	MET (0.37)	TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.