Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25390339 | 0.81 | MAPT (0.33) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL17652009 | 0.80 | KMT2A (0.35) | MEN1KMT2AKDM4E | |
| SCHEMBL17652022 | 0.78 | CHUK (0.43) | KDM4E | |
| SCHEMBL25388131 | 0.76 | HPGD (0.35) | POLBMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL19253836 | 0.74 | TYMS (0.34) | KDM4E | |
| SCHEMBL17652032 | 0.74 | TYMS (0.34) | MEN1KMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL17652035 | 0.74 | LMNA (0.35) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL25389586 | 0.73 | MEN1 (0.38) | MEN1KMT2ARECQL | |
| SCHEMBL5198845 | 0.72 | KDM4E (0.41) | MEN1KMT2ASMN1; SMN2KDM4ETNKS | |
| SCHEMBL5196594 | 0.72 | KDM4E (0.41) | MEN1KMT2ASMN1; SMN2KDM4ETNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11684611-B2 | Compounds for treating diseases associated with a mitochondrial dysfunction | AMABIOTICS (FR) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11684611-B2 | Compounds for treating diseases associated with a mitochondrial dysfunction | NDUFAB1, FH, TFAM | KCNA5 1639/4885POLB 788/4885MEN1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.