SCHEMBL25815389

SCHEMBL25815389

Cc1ccc(C(=O)Nc2ccc(NC(=O)c3ccc(C)c(C)c3)cc2)cc1C

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.72
RAB9A P51151 9/20 0.72
KMT2A Q03164 5/20 0.72
SMN1; SMN2 Q16637 3/20 0.69
MAPT P10636 1/20 0.69
KCNQ3 O43525 1/20 0.67
KCNQ2 O43526 1/20 0.67
TDP1 Q9NUW8 1/20 0.62
MEN1 O00255 3/20 0.60
LMNA P02545 1/20 0.59
THRB P10828 1/20 0.59
FKBP5 Q13451 1/20 0.58
ALDH1A1 P00352 1/20 0.58
TOP1 P11387 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2622747 0.94 NPC1 (0.72) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL22580585 0.94 NPC1 (0.66) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL22580645 0.94 NPC1 (0.66) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL823156 0.94 RAB9A (0.75) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL14291460 0.93 KMT2A (0.69) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL30153426 0.92 FKBP5 (0.63) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL1949548 0.92 FKBP5 (0.63) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL18160357 0.91 KMT2A (0.65) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL2622770 0.91 KMT2A (0.76) NPC1RAB9AKMT2ASMN1; SMN2MAPT
SCHEMBL22746187 0.90 NPC1 (0.72) NPC1RAB9AKMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230231270-A1 Separator and Application Thereof MICROCOSM TECHNOLOGY CO., LTD. (TW) 2023-07-20 US disclosed
EP-4213290-A2 SEPARATOR AND APPLICATION THEREOF Microcosm Technology Co., Ltd. (TW) 2023-07-19 EP disclosed