SCHEMBL1949548

SCHEMBL1949548

Cc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(C)c(C)c3)cc(NC(=O)c3ccc(C)c(C)c3)c2)cc1C

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.63
KCNQ3 O43525 1/20 0.62
KCNQ2 O43526 1/20 0.62
RAB9A P51151 9/20 0.62
NPC1 O15118 8/20 0.62
KMT2A Q03164 6/20 0.62
SMN1; SMN2 Q16637 5/20 0.60
MAPT P10636 3/20 0.60
MEN1 O00255 4/20 0.60
TDP1 Q9NUW8 2/20 0.55
LMNA P02545 2/20 0.55
ALDH1A1 P00352 1/20 0.55
THRB P10828 2/20 0.55
KCNK3 O14649 1/20 0.53
KCNH2 Q12809 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
TP53 P04637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153426 1.00 FKBP5 (0.63) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL13400969 0.94 THRB (0.64) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL10325494 0.93 NPC1 (0.65) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL25815389 0.92 NPC1 (0.72) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL10001978 0.91 FKBP5 (0.63) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL11955302 0.91 THRB (0.69) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL823156 0.90 RAB9A (0.75) FKBP5KCNQ3KCNQ2RAB9ANPC1
SCHEMBL22580645 0.87 NPC1 (0.66) KCNQ3KCNQ2RAB9ANPC1KMT2A
SCHEMBL22580585 0.87 NPC1 (0.66) KCNQ3KCNQ2RAB9ANPC1KMT2A
SCHEMBL2622770 0.87 KMT2A (0.76) FKBP5KCNQ3KCNQ2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP claimed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US claimed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP claimed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US claimed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US claimed
JP-2006518402-A 2006-08-10 JP claimed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP claimed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO claimed
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
CN-103980618-B Single layer and multilayer blown film 巴斯夫欧洲公司 2018-11-13 CN disclosed
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed