SCHEMBL25815497

SCHEMBL25815497

Cc1cccc(-c2cccc(-c3ccccc3-c3cc(C)cc(Cl)c3)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.44
ADORA1 P30542 2/20 0.42
ADORA2A P29274 1/20 0.42
CNR1 P21554 2/20 0.40
PDK2 Q15119 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RPS6KA3 P51812 1/20 0.38
CHRM1 P11229 1/20 0.38
CNR2 P34972 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 2/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
CHEK1 O14757 1/20 0.38
MAP4K4 O95819 1/20 0.38
ABL1 P00519 1/20 0.38
NTRK1 P04629 1/20 0.38
LCK P06239 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815477 0.87 AKR1C2 (0.46) ENPP3ADORA1ADORA2ACNR1L3MBTL1
SCHEMBL23789097 0.85 AKR1C2 (0.47) ENPP3ADORA1ADORA2ACNR1L3MBTL1
SCHEMBL25014732 0.85 AKR1C2 (0.47) ENPP3ADORA1ADORA2ACNR1L3MBTL1
SCHEMBL28414965 0.81 ACHE (0.55) ENPP3ADORA1ADORA2ACNR1PDK2
SCHEMBL27741539 0.80 ESR2 (0.44) ADORA1ADORA2ANPC1RAB9ASMN1; SMN2
SCHEMBL12225753 0.79 RXRA (0.50) CNR1L3MBTL1CNR2NPC1RAB9A
SCHEMBL24689747 0.79 ACHE (0.52) ENPP3ADORA1ADORA2ACNR1PDK2
SCHEMBL12945592 0.78 ADORA2A (0.43) ADORA1ADORA2ACNR1CHRM1CNR2
SCHEMBL21390505 0.77 KDM1A (0.45) ENPP3PDK2RPS6KA3NPC1RAB9A
SCHEMBL5545734 0.77 ESR2 (0.57) CNR1AKR1C2AKR1C1ALDH1A1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189636-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF EMC1, EMC2, EPCAM ENPP3 1354/4885ADORA1 4661/4885ADORA2A 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.