Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815777 | 0.84 | EGFR (0.47) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL25815595 | 0.81 | EGFR (0.51) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL16946787 | 0.80 | SCN9A (0.48) | ADRB2HTR1AEGFRITKCA12 | |
| SCHEMBL13902778 | 0.78 | SCN9A (0.47) | ADRB2HTR1ACA12CA1CA2 | |
| SCHEMBL24838619 | 0.78 | ADRB2 (0.45) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL18569779 | 0.78 | ADRB2 (0.45) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL6276157 | 0.77 | EGFR (0.40) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL18544320 | 0.77 | FDPS (0.59) | KDM4EPOLBALDH1A1 | |
| SCHEMBL12518688 | 0.76 | EGFR (0.53) | ADRB2HTR1AEGFRITKBCHE | |
| SCHEMBL18544359 | 0.76 | FDPS (0.45) | ADRB2HTR1AEGFRITKBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |