Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815595 | 0.85 | EGFR (0.51) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL25815725 | 0.84 | ADRB2 (0.45) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL25815655 | 0.81 | BCHE (0.43) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL25815850 | 0.81 | CA12 (0.47) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL12518688 | 0.81 | EGFR (0.53) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL16946787 | 0.80 | SCN9A (0.48) | EGFRITKADRB2HTR1ASCN9A | |
| SCHEMBL6276157 | 0.79 | EGFR (0.40) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL13883179 | 0.78 | BCHE (0.47) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL13902778 | 0.78 | SCN9A (0.47) | ADRB2HTR1ASCN9ACA12CA1 | |
| SCHEMBL23318482 | 0.77 | ALDH1A1 (0.49) | EGFRITKADRB2HTR1ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |